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Unexpected complications with head and neck hydrogel microsphere particle embolization: A case series and a technical
Naim N Khoury1, Pierre-Olivier Champagne2, Marc Kotowski1
11 Department of Radiology, Centre Hospitalier de l'Universite de Montreal, Canada.
Summary
Endovascular particle embolization using hydrogel microspheres can cause ischemic complications. Researchers suggest oversizing these particles for head and neck procedures to improve safety.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Neurosurgery
Background:
- Endovascular particle embolization is a widely used procedure for various vascular conditions.
- Hydrogel microspheres are increasingly utilized as embolic agents due to their properties.
Observation:
- Four cases of cranial nerve, skin, and mucosal ischemic complications were observed.
- These complications occurred following embolization with 250-500 µm hydrogel microspheres.
Findings:
- Hydrogel microspheres exhibit greater compressibility and penetration potential compared to polyvinyl alcohol particles of similar size.
- This increased potential may contribute to unintended ischemia in adjacent tissues.
Implications:
- Oversizing hydrogel microsphere particles is recommended for head and neck embolizations to mitigate ischemic risks.
- Further research into embolic agent characteristics and procedural optimization is warranted to enhance patient safety.

