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Multishot cartesian turbo spin-echo diffusion imaging using iterative POCSMUSE Reconstruction.

Zhe Zhang1, Bing Zhang2, Ming Li2

  • 1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China.

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|October 28, 2016
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Summary
This summary is machine-generated.

A new diffusion imaging technique using multishot Cartesian turbo spin-echo (TSE) and iterative POCS-based reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE) reduces artifacts. This method provides high-quality diffusion-weighted imaging (DWI) for clearer brain scans.

Keywords:
diffusion phase correctiondiffusion-weighted imagingiterative POCSMUSEmultishot TSE DWIoff-resonance artifacts

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Diffusion-Weighted Imaging (DWI)
  • Image Reconstruction Techniques

Background:

  • Turbo spin-echo (TSE) diffusion-weighted imaging (DWI) is susceptible to off-resonance and motion-induced ghost artifacts.
  • Existing methods like echo-planar imaging (EPI) also suffer from distortions.
  • Accurate DWI is crucial for diagnosing neurological conditions.

Purpose of the Study:

  • To develop and report a novel diffusion imaging technique.
  • To achieve insensitivity to off-resonance and motion-induced ghost artifacts.
  • To improve image quality in multishot Cartesian TSE DWI using iterative POCSMUSE reconstruction.

Main Methods:

  • Phase-insensitive diffusion preparation was employed to address Carr-Purcell-Meiboom-Gill (CPMG) condition violations in TSE DWI.
  • Multishot Cartesian TSE acquisition was used for data readout.
  • Iterative POCS-based reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE) was implemented for phase correction and artifact elimination.

Main Results:

  • The iterative POCSMUSE reconstruction significantly reduced ghost artifacts in multishot TSE DWI.
  • The ghost-to-signal ratio was significantly lower with iterative POCSMUSE (0.0174 ± 0.0024) compared to POCSMUSE (0.0253 ± 0.0040).
  • Image quality scores for multishot TSE DWI were significantly higher than those for single-shot and multishot EPI methods.

Conclusions:

  • The proposed multishot Cartesian TSE DWI with iterative POCSMUSE provides high-quality diffusion images.
  • The technique is insensitive to motion-induced ghost artifacts and off-resonance artifacts.
  • This advancement offers improved diagnostic potential for brain imaging.