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The copper microRNAs.

Marinus Pilon1

  • 1Biology Department, Colorado State University, Fort Collins, CO, 80523, USA.

The New Phytologist
|October 22, 2016
PubMed
Summary
This summary is machine-generated.

Copper (Cu) microRNAs are upregulated during Cu deficiency and play roles in plant stress tolerance. A new model highlights their mobile nature in regulating copper homeostasis and plant-microbe interactions.

Keywords:
copper (Cu)copper deficiencycopper microRNAcopper prioritizationphotosynthesissquamosa promoter binding protein-like (SPL7)

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Area of Science:

  • Plant molecular biology
  • Nutrient homeostasis
  • Plant-microbe interactions

Background:

  • Copper (Cu) microRNAs are upregulated by Cu deficiency, regulating Cu protein synthesis.
  • Mutant and over-expression studies suggest roles in abiotic stress tolerance.
  • Existing data present a complex picture of Cu microRNA function.

Purpose of the Study:

  • To reconcile divergent findings on copper microRNA function.
  • To propose a model emphasizing the mobile nature of copper microRNAs.
  • To explore the role of copper microRNAs in plant-microbe interactions.

Main Methods:

  • Expression analysis of copper microRNA mutants and over-expressors.
  • Phenotypic analysis under various stress conditions.
  • Development of a conceptual model for copper microRNA regulation.

Main Results:

  • Copper microRNAs are involved in both copper homeostasis and abiotic stress tolerance.
  • A model proposing cell-to-cell mobility of copper microRNAs is presented.
  • Copper microRNA regulatory circuits are potentially co-opted for plant-microbe interactions.

Conclusions:

  • Copper microRNAs are mobile molecules crucial for copper homeostasis.
  • These regulatory circuits extend to plant interactions with microbes.
  • Further research on mobile copper microRNAs will illuminate plant development and nutrition integration.