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Updated: Mar 13, 2026

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Bridging the gap: Hybrid cardiac echo in the critically ill.
Jacob J Glaser1, Cassandra Cardarelli, Samuel Galvagno
1From the Division of Trauma and Surgical, Critical Care (J.J.G., T.M.S., S.B.M.), Department of Surgery, and Department of Anesthesiology (S.G.), University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore; and Walter Reed National Military Medical Center (C.C.), Bethesda, Maryland.
The Focused Rapid Echocardiographic Examination (FREE) correlates well with standard transthoracic echocardiography (TTE) for assessing cardiac function. This hybrid ultrasound provides actionable data for critically ill patients, especially in resource-limited settings.
Area of Science:
- Point-of-care ultrasound
- Cardiac imaging
- Critical care medicine
Background:
- Point-of-care ultrasound (POCUS) is vital for critically ill patients but often lacks the quantitative detail of transthoracic echocardiography (TTE).
- The Focused Rapid Echocardiographic Examination (FREE) was developed as a hybrid POCUS tool emphasizing cardiac function over detailed anatomy.
- FREE aims to provide actionable clinical data comparable to TTE.
Purpose of the Study:
- To evaluate the correlation between quantitative measurements obtained from FREE and standard TTE.
- To determine if FREE provides clinically useful information for decision-making in critically ill patients.
Main Methods:
- A cohort of patients who underwent both FREE and TTE on the same day was identified.
- Quantitative cardiac function parameters, including ejection fraction, diastolic function, and right ventricular function, were measured using both FREE and TTE.
- Correlation analyses were performed to compare measurements between the two echocardiographic modalities.
Main Results:
- FREE demonstrated strong correlations with TTE for ejection fraction (r=0.89) and other key parameters like left ventricular internal dimension end diastole (r=0.94).
- Right ventricular function agreement was observed in 82% of patients, and pericardial effusion detection showed 94% concordance.
- FREE effectively assessed cardiac function without missing significant valvular anatomy.
Conclusions:
- The FREE examination provides a functional cardiac assessment that strongly correlates with TTE measurements.
- FREE offers significant clinical value for critically ill patients, particularly in remote or resource-limited environments.
- This hybrid ultrasound approach enhances clinical decision-making by offering rapid, actionable cardiac insights.
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