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[Negative post-ischemic T waves in variant angina].

F Prati1, A Maddaluna, A Pellegrini

  • 1Divisione di Cardiologia A, Ospedale San Camillo, Roma.

Giornale Italiano Di Cardiologia
|March 1, 1989
PubMed
Summary
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Negative T waves in variant angina patients indicate significant coronary artery stenosis, particularly in inferior leads. Anterior lead T waves show less accuracy for left anterior descending artery issues.

Area of Science:

  • Cardiology
  • Clinical Electrophysiology
  • Diagnostic Imaging

Context:

  • The prognostic value of negative T waves in unstable angina is debated.
  • Limited data exists on negative T waves in variant angina patients.
  • Electrocardiographic (ECG) findings in variant angina require further investigation.

Purpose:

  • To assess the significance of negative post-ischemic T waves in variant angina.
  • To correlate ECG findings with coronary angiography results.
  • To evaluate the diagnostic accuracy of negative T waves for coronary artery stenosis.

Summary:

  • Negative T waves were observed in 53% of variant angina patients.
  • Holter monitoring revealed no significant differences in ischemic events or arrhythmias between patients with or without negative T waves.

Related Experiment Videos

  • Negative T waves in inferior leads demonstrated high sensitivity (85%) and specificity (80%) for right coronary artery and/or circumflex artery stenosis.
  • Anterior lead negative T waves showed moderate sensitivity (54%) and low specificity (43%) for left anterior descending coronary artery stenosis.
  • Impact:

    • Negative T waves, especially in inferior leads, are valuable indicators of significant coronary artery stenosis in variant angina.
    • This study refines the diagnostic utility of ECG findings in variant angina.
    • Findings can aid in risk stratification and management of patients with variant angina.