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Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development
Published on: June 19, 2018
New Cutaneous Vaccine Adjuvant that STINGs a Little Less
Stephan M Caucheteux1, Vincent Piguet1
1Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Abstract:
Cutaneous vaccination can be a challenge because the development of local skin inflammation is often unavoidable. Thus, it is important to identify and validate new vaccine adjuvants that enhance immunization without the burden of inflammation. Wang et al. now report on a cyclic GMP-AMP adjuvant, the natural stimulator of interferon genes agonist, providing evidence for potent immune responses without inflammation.
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