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Updated: Mar 13, 2026
Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding
Published on: June 27, 2014
Low-temperature deposition manufacturing: A novel and promising rapid prototyping technology for the fabrication of
Wei Liu1, Daming Wang2, Jianghong Huang3
1Shenzhen Key Laboratory of Tissue Engineering, Shenzhen Second People's Hospital, Shenzhen 518035, China; Shenzhen Laboratory of Digital Orthopeadic Engineering, Shenzhen Second People's Hospital, Shenzhen 518035, China; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Shenzhen Centre of Sports Medicine & Engineering Technology, Shenzhen Second People's Hospital, Shenzhen 518035, China.
Abstract:
Developed in recent years, low-temperature deposition manufacturing (LDM) represents one of the most promising rapid prototyping technologies. It is not only based on rapid deposition manufacturing process but also combined with phase separation process. Besides the controlled macropore size, tissue-engineered scaffold fabricated by LDM has inter-connected micropores in the deposited lines. More importantly, it is a green manufacturing process that involves non-heating liquefying of materials. It has been employed to fabricate tissue-engineered scaffolds for bone, cartilage, blood vessel and nerve tissue regenerations. It is a promising technology in the fabrication of tissue-engineered scaffold similar to ideal scaffold and the design of complex organs. In the current paper, this novel LDM technology is introduced, and its control parameters, biomedical applications and challenges are included and discussed as well.
