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Related Experiment Video

Updated: Mar 13, 2026

Errors as a Means of Reducing Impulsive Food Choice
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Are ethics promulgations self-defeating?

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  • 1Department of Philosophy, Carnegie Mellon University, Baker Hall 161A, Pittsburgh, PA 15219, USA.

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|July 19, 2015
PubMed
Summary
This summary is machine-generated.

Ethical standards in international clinical research may harm, not help, subjects in low- and middle-income countries (LMICs). This analysis argues non-exploitation is a key ethical goal, independent of other interests, and questions sponsor obligations.

Keywords:
exploitationresearch ethics

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Area of Science:

  • Bioethics
  • Clinical Research Ethics
  • Global Health Ethics

Background:

  • International clinical research ethical standards aim to protect subjects in low- and middle-income countries (LMICs).
  • Alan Wertheimer posits these standards may be self-defeating, increasing research costs and potentially harming LMIC subjects.
  • The author challenges Wertheimer's non-deontological critique of these ethical standards.

Purpose of the Study:

  • To analyze the ethical implications of international clinical research standards in LMICs.
  • To re-evaluate the deontological basis of non-exploitation in research ethics.
  • To challenge the assumption that exploitative practices in research are justifiable if they benefit LMIC populations.

Main Methods:

  • Philosophical analysis of ethical arguments regarding international clinical research.
  • Deconstruction of Alan Wertheimer's critique of ethical standards promulgation.
  • Examination of the principle of non-exploitation in bioethics.

Main Results:

  • Wertheimer's argument against deontological ethical standards is found to be question-begging.
  • Non-exploitation is identified as a crucial ethical goal, sometimes superseding the promotion of LMIC interests.
  • The author suggests a re-evaluation of the perceived lack of pre-existing obligations for wealthy sponsors to aid LMIC populations.

Conclusions:

  • Ethical standards in international clinical research require careful consideration to avoid unintended negative consequences.
  • The principle of non-exploitation holds significant ethical weight, independent of other utilitarian considerations.
  • A critical reassessment of sponsor responsibilities in global health research is warranted.