Related Experiment Video

Updated: Mar 13, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

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Acute myocardial infarction in a patient with sickle cell trait

Oğuz Akkuş1, Mustafa Topuz2, Ali Deniz3

  • 1Department of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|October 25, 2016
PubMed

Insights

Sickle cell trait (HbAS) can rarely cause acute myocardial infarction in young adults. Prompt treatment restored blood flow and relieved symptoms in a recent case.

Area of Science:

  • Cardiology
  • Hematology
  • Genetics

Background:

  • Sickle cell trait (HbAS) is generally considered benign.
  • Myocardial infarction (MI) in young adults is uncommon and often associated with traditional risk factors.

Observation:

  • A young adult patient presented with acute inferior myocardial infarction.
  • Coronary angiography revealed microemboli in the circumflex artery.

Findings:

  • Sickle cell trait (HbAS) was identified as the underlying pathology.
  • Treatment with anticoagulant and anti-aggregant therapies successfully restored coronary artery flow.
  • The patient's ST segments normalized, and symptoms resolved.

Implications:

  • This case highlights a rare but serious complication of HbAS.
  • It underscores the importance of considering HbAS in young MI patients.
  • Early diagnosis and management are crucial for favorable outcomes in such cases.

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