Related Experiment Video
Updated: Mar 13, 2026

Location, Dissection, and Analysis of the Murine Stellate Ganglion
Published on: December 22, 2020
[Left cardiac sympathetic denervation in congenital ventricular arrythmias: initial experience]
X Tarrado1, G Sarquella-Brugada2, L Saura1
1Servicio de Cirugía Pediátrica. Hospital Sant Joan de Déu-Clínic. Universidad de Barcelona.
Background:
Left cardiac sympathetic denervation (LCSD) has been proposed as a second-line therapy for potentially lethal ventricular arrythmia with no response to the gold standard treatment with beta-blockers. It has been used mainly in channelopathies such as long QT syndrome (LQTS) and polymorphic cathecolaminergic ventricular tachycardia (PCVT).
Aim:
Analizing our preliminary experience in the treatment of congenital ventricular arrythmia with thoracoscopic LCSD.
Material And Methods:
We have reviewed the first 5 LCSD performed in the last two years (2011-2013) to 5 female patients with a mean age of 8 years (1 month-15 years). The underlying disease was the LQTS in three and the PCVT in two.
Results:
Selective contralateral bronchial intubation was used in two cases and double-lumen tube in three. We performed in all cases T1 sympathicolysis, denervation of T2 ganglion and sympathicolysis of T3 and T5 levels. No intraoperatory nor postoperatory complications were observed. In four cases ventricular tachycardia disappeared after the procedure and in one case, although they did not completely disappeared, they could be better controled on medical therapy. Ventricular extrasystoles reappeared 17 months after the procedure in one PCTV case, but disappeared completely after T1-T5 left sympathectomy completion. With a mean follow-up time of 20 months, all patients are sympthom-free and continue on betablocker oral therapy.
Conclusions:
Thoracoscopic DCSI is a safe and effective therapy for prevention of severe congenital ventricular arrythmias.
More Related Videos
06:40Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System
Published on: May 22, 2018
09:36Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
Related Concept Videos
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Heart Failure II: Pathophysiology
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Heart Failure Drugs: β-Blockers
Cardiomyopathy IV: Restrictive Cardiomyopathy