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Fatal coronary sinus thrombosis due to hypercoagulability in Crohn's disease

Janet Martin1, Vidhya Nair2, Allison Edgecombe2

  • 1Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada L8S 4L8.

Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology
|October 25, 2016
PubMed

Insights

A young man with Crohn's disease died suddenly from coronary sinus thrombosis, a rare condition. This case highlights the need for autopsy in patients with hypercoagulable states.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Pathology

Background:

  • Crohn's disease is a chronic inflammatory condition that can lead to various complications.
  • Coronary sinus thrombosis is a rare but serious condition, typically linked to cardiac procedures.

Observation:

  • A 27-year-old male with a psoas muscle abscess due to Crohn's disease experienced sudden death during hospitalization.
  • A medicolegal autopsy revealed thrombosis within the coronary sinus.

Findings:

  • This is the first reported case of coronary sinus thrombosis associated with Crohn's disease.
  • The autopsy identified coronary sinus thrombosis as the cause of sudden death.

Implications:

  • The findings suggest a potential link between Crohn's disease and coronary sinus thrombosis.
  • Autopsy examination of the coronary sinus is recommended for patients with hypercoagulable states, including those with Crohn's disease.

Keywords:
AutopsyCoronary sinus thrombosisCrohn's diseaseHypercoaguability

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