Comparing pattern scanning laser trabeculoplasty to selective laser trabeculoplasty: A randomized controlled trial

Area of Science:

• Ophthalmology
• Glaucoma treatment
• Laser therapy

Background:

• Glaucoma is a leading cause of irreversible blindness worldwide.
• Intraocular pressure (IOP) is a primary modifiable risk factor for glaucoma progression.
• Laser trabeculoplasty is a common treatment to lower IOP in open-angle glaucoma.

Purpose of the Study:

• To compare the safety, tolerability, and IOP-lowering efficacy of pattern scanning laser trabeculoplasty (PSLT) versus selective laser trabeculoplasty (SLT).
• To evaluate these outcomes in fellow eyes of untreated glaucoma patients.

Main Methods:

• A randomized controlled trial involving 29 patients with open-angle glaucoma.
• Each patient received either PSLT or SLT in one eye.
• Intraocular pressure (IOP) and patient comfort (Visual Analogue Scale - VAS) were assessed over 6 months.

Main Results:

• Both PSLT and SLT demonstrated comparable safety and IOP reduction.
• PSLT showed a statistically significant greater IOP reduction at 1 and 3 months compared to SLT.
• Patients reported significantly better comfort with PSLT (lower VAS scores) than with SLT.

Conclusions:

• Both PSLT and SLT are safe and effective for lowering IOP in glaucoma patients.
• PSLT provides superior patient tolerability and comfort compared to SLT.
• PSLT may be a preferred option for patients sensitive to treatment discomfort.