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Aqueous humour outflow improvement after excimer laser trabeculostomy
Martin Kallab1, Isabella Vieboeck1, Parsa Panahi1
1Ophthalmology/Optometry, Johannes Kepler Universitat, Linz, Austria.
The British Journal of Ophthalmology
|February 18, 2026
Summary
The Elios glaucoma procedure (excimer laser trabeculostomy, ELT) significantly improved aqueous humour outflow (AHO) in patients. This enhancement in AHO was observed even beyond the treated areas, suggesting broader effects.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Surgical Innovation
Background:
- Glaucoma management requires effective methods to improve aqueous humour outflow (AHO).
- The Elios glaucoma procedure, utilizing excimer laser trabeculostomy (ELT), is a novel surgical approach.
- Understanding the impact of ELT on AHO is crucial for its clinical application.
Purpose of the Study:
- To investigate changes in aqueous humour outflow (AHO) following the Elios glaucoma procedure (excimer laser trabeculostomy, ELT).
- To assess AHO using sequential angiography after combining ELT with cataract surgery.
Main Methods:
- Aqueous humour outflow (AHO) angiography was performed in six eyes of five patients.
- Two different tracers were employed for sequential AHO angiography.
- AHO was specifically compared in the nasal quadrant regions of interest.
Main Results:
- AHO demonstrated a statistically significant improvement post-ELT (p=0.03).
- All patients exhibited individual, qualitative improvements in AHO.
- Observed AHO enhancement extended beyond the direct application site of the ELT.
Conclusions:
- The Elios glaucoma procedure (excimer laser trabeculostomy, ELT) leads to significant aqueous humour outflow (AHO) improvement.
- ELT may induce AHO changes beyond the treated area.
- Further research is necessary to correlate AHO improvements with clinical efficacy.
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