Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Flow01:29

Blood Flow

77.4K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
77.4K
Fetal Circulation01:14

Fetal Circulation

4.0K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
4.0K
Capillary Beds01:20

Capillary Beds

7.7K
Capillary beds are networks of tiny blood vessels that play a crucial role in the circulatory system. These beds are where the exchange of gases, nutrients, and waste products occurs between the blood and surrounding tissues. Each capillary bed consists of numerous capillaries, which are the smallest blood vessels in the body, typically only one cell-thick. This thinness allows for the efficient diffusion of substances.
Capillaries connect arterioles, small branches of arteries, to venules,...
7.7K
Development of Blood Vessels01:07

Development of Blood Vessels

1.7K
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
1.7K
Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

8.6K
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
8.6K
Capillaries and Their Types01:20

Capillaries and Their Types

8.6K
Capillaries, a crucial constituent of the circulatory system, are diminutive vessels with a diameter between 5–10 micrometers, accommodating perfusion to the tissues through the phenomenon known as microcirculation. Through their permeable walls, consisting of an endothelial layer ensconced by a basement membrane and sporadically dispersed smooth muscle fibers, the exchange of substances between the blood and the interstitial fluid becomes plausible. Variance in wall composition exists,...
8.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Levels of complement factor H-related 4 protein do not influence susceptibility to age-related macular degeneration or its course of progression.

Nature communications·2024
Same author

A case of melanocytomalytic glaucoma.

Journal francais d'ophtalmologie·2022
Same author

Cutaneous melanoma metastatic to the conjunctiva.

Journal francais d'ophtalmologie·2022
Same author

Could Extension Into the Lacrimal Gland and Sac Thwart Topical Chemotherapy for Intraepithelial Sebaceous Carcinoma?

Ophthalmic plastic and reconstructive surgery·2021
Same author

Narrow escape problem for Brownian particles in a microsphere with internal circulation.

Physical review. E·2019
Same author

Environmental policy constraints for acidic exhaust gas scrubber discharges from ships.

Marine pollution bulletin·2014

Related Experiment Video

Updated: Mar 13, 2026

Spatial Temporal Analysis of Fieldwise Flow in Microvasculature
09:39

Spatial Temporal Analysis of Fieldwise Flow in Microvasculature

Published on: November 18, 2019

6.3K

Form, shape and function: segmented blood flow in the choriocapillaris.

M A Zouache1, I Eames2, C A Klettner2

  • 1University College London, Institute of Ophthalmology, London, EC1V 9EL, United Kingdom.

Scientific Reports
|October 26, 2016
PubMed
Summary

The unusual planar geometry of the retinal choriocapillaris divides blood flow into distinct segments. This segmentation limits diffusion and impacts how nutrients reach the outer retina.

More Related Videos

Intravital Video Microscopy Measurements of Retinal Blood Flow in Mice
10:16

Intravital Video Microscopy Measurements of Retinal Blood Flow in Mice

Published on: December 26, 2013

6.2K
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

2.2K

Related Experiment Videos

Last Updated: Mar 13, 2026

Spatial Temporal Analysis of Fieldwise Flow in Microvasculature
09:39

Spatial Temporal Analysis of Fieldwise Flow in Microvasculature

Published on: November 18, 2019

6.3K
Intravital Video Microscopy Measurements of Retinal Blood Flow in Mice
10:16

Intravital Video Microscopy Measurements of Retinal Blood Flow in Mice

Published on: December 26, 2013

6.2K
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

2.2K

Area of Science:

  • Physiology
  • Biophysics
  • Vascular Biology

Background:

  • Fluid transport systems are crucial for animal and plant life.
  • Vertebrate vascular systems typically exhibit branched geometries.
  • The outer retina's maintenance relies on the planar choriocapillaris microvascular bed.

Purpose of the Study:

  • To investigate the flow and mass transfer properties of the choriocapillaris's planar topology.
  • To understand how this unique geometry influences blood flow and metabolite delivery.
  • To establish a framework for studying the outer retina's metabolite delivery system.

Main Methods:

  • Analysis of fluid dynamics within the choriocapillaris geometry.
  • Modeling of blood flow patterns and separation surfaces.
  • Examination of mass transfer and diffusion-limited transport.

Main Results:

  • Blood flow in the choriocapillaris is divided into functional segments by separation surfaces.
  • Transport of passive substances near these surfaces is diffusion-limited.
  • Mass exchange with the outer retina is dependent on the shape of these functional segments.

Conclusions:

  • The planar choriocapillaris geometry creates a unique system for metabolite delivery to the outer retina.
  • Functional segment shape dictates mass exchange efficiency.
  • This study provides a novel framework for investigating retinal vascular health and disease.