Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell Adhesion in Plants01:14

Cell Adhesion in Plants

3.5K
Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
3.5K
Cell Adhesion Molecules - Types and Functions01:20

Cell Adhesion Molecules - Types and Functions

10.4K
Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
The Integrin family of proteins is primarily  involved...
10.4K
Cell Adhesion Molecules - Types and Functions01:20

Cell Adhesion Molecules - Types and Functions

4.4K
4.4K
Overview of Cell-Matrix Interactions01:24

Overview of Cell-Matrix Interactions

9.6K
The extracellular matrix or ECM holds cells together to form a tissue and allows the cells within the tissue to communicate. ECM comprises proteins such as fibronectin, collagen, laminin, etc. The most abundant protein in this space is collagen. Collagen fibers are interwoven with carbohydrate-containing protein molecules called proteoglycans. ECM allows cell migration and provides a structural scaffold at cell adhesion that anchors the cell when the extracellular matrix proteins interact with...
9.6K
Actin Polymerization and Cell Motility01:13

Actin Polymerization and Cell Motility

7.0K
Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate....
7.0K
Adhesion01:14

Adhesion

45.3K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
45.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of High-Intensity Interval Training on Cardiopulmonary Function in Patients with Acute Myocardial Infarction with and without Cardiac Arrest: A Retrospective Study.

International journal of general medicine·2026
Same author

Micronutrient deficiencies and CVD: a binational analysis of National Health and Nutrition Examination Survey (NHANES) and China Health and Retirement Longitudinal Study (CHARLS).

The British journal of nutrition·2026
Same author

Caspofungin-Based Red-Emissive Probes for Fluorescent Imaging of Pathogenic Fungi.

JACS Au·2026
Same author

Advanced single-cell transcriptomics deciphers cellular complexity and MIF-orchestrated signaling networks in diabetes-induced myocardial disease.

SLAS technology·2026
Same author

Surface-Initiated PET-RAFT Enables In Situ Glycopolymer Microarrays for Live-Cell Glycan Profiling and Programmable Biointerfaces.

Biomacromolecules·2026
Same author

Structure-Property Relationships of Near-Infrared Cyanine Dyes: Chalcogen-Driven Singlet Oxygen Generation with High Fluorescence Efficiency.

ACS omega·2026
Same journal

AI-Derived Smart Microneedle Systems for Advanced Wound Management: From Intelligent Sensing to Closed-Loop Therapy.

Macromolecular bioscience·2026
Same journal

A Novel Chitosan-Gelatin Scaffold and Cell Spray Therapy for Treating Limbal Stem Cell Deficiency.

Macromolecular bioscience·2026
Same journal

Electroconductive Soft Microcarriers for Suspension Culture of Skeletal Muscle Cells.

Macromolecular bioscience·2026
Same journal

Dual-Responsive Chitosan-Grafted PNIPAAm Hydrogel Eye Drop Incorporating Insulin-Imprinted Microgels for Dry Eye Syndrome Treatment.

Macromolecular bioscience·2026
Same journal

Levan Inspired Hybrid Composites Materials: Bridging Natural Polysaccharides with Biomedical Technology.

Macromolecular bioscience·2026
Same journal

Anion-Specific Mechanisms in Fibrinogen Self-Assembly: Contrasting Effects of Phosphates and Chlorides in Nanofiber Formation.

Macromolecular bioscience·2026
See all related articles

Related Experiment Video

Updated: Mar 13, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
10:34

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Published on: April 23, 2017

7.3K

Understanding Polymer-Cell Attachment.

Andrea Venturato1, Gillian MacFarlane1, Jin Geng1

  • 1School of Chemistry, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh, EH9 3KJ, UK.

Macromolecular Bioscience
|October 26, 2016
PubMed
Summary
This summary is machine-generated.

Researchers synthesized novel polymeric materials to understand cell adhesion. Both HeLa and HEK cells preferred moderately hydrophobic polymers, paving the way for advanced biomaterial scaffolds.

Keywords:
SET-LRPblock copolymercontrolled living polymerizationpolymer-cell interactionsurface chemistry

More Related Videos

Wet Chemistry and Peptide Immobilization on Polytetrafluoroethylene for Improved Cell-adhesion
06:15

Wet Chemistry and Peptide Immobilization on Polytetrafluoroethylene for Improved Cell-adhesion

Published on: August 15, 2016

8.2K
Characterization of Cell Membrane Extensions and Studying Their Roles in Cancer Cell Adhesion Dynamics
08:11

Characterization of Cell Membrane Extensions and Studying Their Roles in Cancer Cell Adhesion Dynamics

Published on: March 26, 2018

8.8K

Related Experiment Videos

Last Updated: Mar 13, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
10:34

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Published on: April 23, 2017

7.3K
Wet Chemistry and Peptide Immobilization on Polytetrafluoroethylene for Improved Cell-adhesion
06:15

Wet Chemistry and Peptide Immobilization on Polytetrafluoroethylene for Improved Cell-adhesion

Published on: August 15, 2016

8.2K
Characterization of Cell Membrane Extensions and Studying Their Roles in Cancer Cell Adhesion Dynamics
08:11

Characterization of Cell Membrane Extensions and Studying Their Roles in Cancer Cell Adhesion Dynamics

Published on: March 26, 2018

8.8K

Area of Science:

  • Polymer chemistry and biomaterials science.
  • Investigating cell-surface interactions for material design.

Background:

  • Developing polymeric materials with controlled cell adhesion is crucial for tissue engineering and regenerative medicine.
  • Cell-surface interactions are complex and depend on factors like cell type and material properties.

Purpose of the Study:

  • To synthesize and characterize random and block copolymers of 2-(dimethylamino)ethyl acrylate and ethyl acrylate.
  • To investigate the correlation between polymer composition, chain length, and cell attachment for HeLa and HEK cells.
  • To establish a model for predicting cell attachment based on material properties.

Main Methods:

  • Synthesis of copolymers using single electron transfer living radical polymerization.
  • Characterization of polymer composition and polydispersity.
  • Evaluation of HeLa and HEK cell attachment and growth on synthesized polymer surfaces.

Main Results:

  • Polymers with highly defined monomer compositions and narrow polydispersity indices were successfully synthesized.
  • Cell attachment was successfully modeled based on monomer composition and polymer chain length.
  • Both HeLa and HEK cells demonstrated preferential attachment to moderately hydrophobic polymer surfaces.

Conclusions:

  • Understanding biological-material interactions is key to designing functional polymer scaffolds.
  • Moderately hydrophobic polymeric materials show promise for controlled cell adhesion.
  • This study provides a foundation for engineering biomaterials with predictable cell binding capabilities.