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Updated: Mar 13, 2026

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
Published on: May 12, 2023
[Research Progress of Necroptosis in Hematological Malignancies -Review]
Zuo-Fei Chi1, Wei Yang2, Qiu-Ying He1
1Department of Pediatric Hematology,Shengjing Hospital of China Medical University,Shenyang 110022, Liaoning Province, China.
Abstract:
Necroptosis is a novel programmed cell death mechanism which is characterized by a necrotic morphology, but the necroptosis is precisely regulated by cellular signaling pathway just like apoptosis. Recently, many reports have revealed that necroptosis contributes to the pathogenesis of inflammation, ischemic reperfusion injury and tumour. Hematological malignancies are a set of hemotopathy diseases with poor prognosis. In this review, the research progress of signaling pathway of necroptosis and its role in hematological malignancies are summarized.
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