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Updated: Mar 13, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Adult Manifestation of Henoch-Schönlein Purpura
Daria Marley Kemp1, James Studdiford2, Katie Osley3
1Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical Collage at Thomas Jefferson University, Philadelphia, PA; daria.kemp@jefferson.edu.
Abstract:
A 51-year-old man initially presented to the hospital with a 2-week history of constipation, intermittently diffuse abdominal pain, nausea, vomiting, and productive cough. Results from chest x-ray and obstruction series appreciated a right lower lobe opacity and small right pleural effusion. The patient met sepsis criteria and was empirically covered for community-acquired pneumonia with vancomycin, piperacillin-tazobactam, moxifloxacin, and tobramycin. His hospital course was complicated by oliguria, acute kidney injury with a normal renal ultrasound, and transaminitis with a negative hepatitis panel. After clinical improvement, he was discharged on 2 additional days of levofloxacin to complete a 7-day antibiotic course.
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