pyGeno: A Python package for precision medicine and proteogenomics
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Updated: Mar 13, 2026

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
Published on: May 22, 2018
Tariq Daouda1, Claude Perreault2, Sébastien Lemieux3
1Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada; Department of Biochemistry, Faculty of Medicine, Université de Montréal, Montreal, Canada.
Abstract:
pyGeno is a Python package mainly intended for precision medicine applications that revolve around genomics and proteomics. It integrates reference sequences and annotations from Ensembl, genomic polymorphisms from the dbSNP database and data from next-gen sequencing into an easy to use, memory-efficient and fast framework, therefore allowing the user to easily explore subject-specific genomes and proteomes. Compared to a standalone program, pyGeno gives the user access to the complete expressivity of Python, a general programming language. Its range of application therefore encompasses both short scripts and large scale genome-wide studies.
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