Related Experiment Video
Updated: Mar 13, 2026
06:18
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
9.7K
Medication-Related Pseudotumor Cerebri Syndrome
Olga R Thon1, John W Gittinger1
1a Department of Ophthalmology , Massachusetts Eye and Ear Infirmary , Boston , MA , USA.
Seminars in Ophthalmology
|October 28, 2016
Summary
Pseudotumor cerebri syndrome, characterized by increased intracranial pressure, can be linked to certain medications. This review examines the evidence connecting various drugs to this neurological condition.
Area of Science:
- Neurology
- Ophthalmology
- Pharmacology
Background:
- Pseudotumor cerebri syndrome (PTCS) involves elevated intracranial pressure (ICP) and papilledema.
- The exact cause of PTCS is often unknown, but medication associations are increasingly recognized.
Purpose of the Study:
- To systematically review and evaluate the evidence linking specific medications to the development of pseudotumor cerebri syndrome.
- To consolidate current knowledge on drug-induced PTCS.
Main Methods:
- Comprehensive literature search for case reports and case series.
- Evaluation of the quality and strength of evidence for medication-PTCS associations.
Main Results:
- Several medications have been anecdotally or strongly associated with PTCS over recent decades.
- Evidence varies in strength, with some drugs showing a more consistent link than others.
Conclusions:
- Medication-induced PTCS is a significant clinical consideration.
- Further research may be needed to clarify causal relationships and establish diagnostic criteria for drug-associated PTCS.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
01:28Angle Closure Glaucoma: Treatment
1.5K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.5K
01:25Glaucoma: Overview
1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
01:15Equilibrium and Balance
7.6K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
7.6K