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Acute kidney injury in a patient with hemolytic anemia and thrombocytopenia

Michael Breunig1, Miguel Lalama, Gabrielle Rivard

  • 1At the Mayo Clinic in Rochester, Minn., Michael Breunig practices hospital internal medicine and Miguel Lalama is an associate clinical consultant. Gabrielle Rivard practices at Allina Health Clinic: Ear, Nose, and Throat in St. Paul, Minn. Deanne Kashiwagi is a consultant in the Division of Hospital Internal Medicine at the Mayo Clinic. Lynn Cornell is a consultant in the Division of Anatomic Pathology at the Mayo Clinic. The authors have disclosed no potential conflicts of interest, financial or otherwise.

JAAPA : Official Journal of the American Academy of Physician Assistants
|October 28, 2016
PubMed

Atypical hemolytic uremic syndrome (HUS) is clinically difficult to distinguish from HUS and thrombotic thrombocytopenic purpura. Atypical HUS results from dysregulation of complement activation causing thrombotic microangiopathy affecting multiple organ systems. Atypical HUS is associated with high morbidity and mortality, making early recognition and appropriate therapy necessary to improve patient outcomes.

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