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Related Experiment Video

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In Vivo Methods to Assess Retinal Ganglion Cell and Optic Nerve Function and Structure in Large Animals

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Where the Name "GOR" Originates: A Story.

¹IUPAB, International Council for Science (ICSU), 5 rue Auguste Vacquerie, Paris, 75116, France. jgarnier@icsu.org.

Methods in Molecular Biology (Clifton, N.J.)

|October 28, 2016

Summary

This summary is machine-generated.

The GOR program predicts protein secondary structures using information theory. Developed in 1978, this bioinformatics tool remains available today.

Keywords:

GOR Information theory Protein structure prediction Secondary structure prediction

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Area of Science:

Bioinformatics
Computational Biology
Structural Biology

Background:

The GOR program, developed in 1978, utilizes information theory for protein secondary structure prediction.
This early bioinformatics tool has remained in distribution since its inception.
Its creation highlights the influence of scientific collaboration and technological advancements.

Purpose of the Study:

To describe the development and legacy of the GOR program for protein secondary structure prediction.
To illustrate the impact of personal scientific endeavors, opportunities, and emerging technologies on bioinformatics tool development.

Main Methods:

The GOR program employs the theory of information to predict secondary structures from amino acid sequences.
Utilized computational methods prevalent in the late 1970s for sequence analysis.

Main Results:

The GOR program successfully predicted protein secondary structures based on amino acid sequences.
Demonstrated the feasibility of applying information theory to biological sequence analysis.

Conclusions:

The GOR program's enduring availability showcases its foundational contribution to bioinformatics.
The development narrative underscores the significance of intrinsic motivation and collaborative spirit in scientific innovation, independent of external funding.