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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
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Related Experiment Video

Updated: Mar 12, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

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Collapsing glomerulopathy associated with pulmonary tuberculosis.

N D Srinivasaprasad1, G Chandramohan1, V Praveen1

  • 1Department of Nephrology, Stanley Medical College, Chennai, Tamil Nadu, India.

Indian Journal of Nephrology
|November 1, 2016
PubMed
Summary
This summary is machine-generated.

Collapsing glomerulopathy, a severe kidney disease, was linked to pulmonary tuberculosis in a patient. Treatment with antitubercular therapy and steroids led to partial kidney function recovery and dialysis independence.

Keywords:
Collapsing glomerulopathyheavy proteinuriapulmonary tuberculosisrenal failure

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Area of Science:

  • Nephrology
  • Pulmonology
  • Infectious Diseases

Background:

  • Collapsing glomerulopathy (CG) is a severe kidney injury characterized by glomerular damage.
  • CG often presents with nephrotic-range proteinuria and acute kidney injury, typically requiring dialysis.
  • Associations between CG and various systemic conditions are documented, but its link with tuberculosis is less common.

Observation:

  • A unique case presented involving a patient with collapsing glomerulopathy and concurrent pulmonary tuberculosis.
  • The patient exhibited significant proteinuria and severe renal failure necessitating dialysis.
  • This presentation highlights an unusual comorbidity between a glomerular disease and a pulmonary infection.

Findings:

  • Antitubercular therapy combined with oral steroid administration was initiated for the patient.
  • Following treatment, the patient demonstrated partial recovery of glomerular filtration rate.
  • The patient became independent of dialysis, indicating a positive treatment response.

Implications:

  • This case suggests a potential link between pulmonary tuberculosis and collapsing glomerulopathy.
  • Combined treatment strategies involving antitubercular agents and immunosuppressants may be beneficial in such cases.
  • Further research and long-term follow-up are essential to understand the disease progression and treatment efficacy.