Related Experiment Video
Updated: Mar 12, 2026

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
Published on: June 6, 2025
Erosive effects of pediatric liquid medicinal syrups on primary enamel: An in vitro comparative study
Parimala Kulkarni1, Ayushi Anand1, Arpana Bansal1
1Department of Pedodontics and Preventive Dentistry, People's Dental Academy, Bhopal, Madhya Pradesh, India.
Context:
The use of liquid medicinal syrups in childhood is high owing to the reasons that children suffer from illness quite often. The acidic component in the formulations may cause erosion to the dental tissues.
Aims:
The aim of this study is to evaluate the erosive potential of pediatric liquid medicinal syrups on the deciduous teeth.
Subjects And Methods:
A total of sixty extracted/exfoliated noncarious deciduous molars were used. Four medical syrups were used (viz., 1 - artificial saliva [control], 2 - Ferium XT, 3 - Crocin syrup, 4 - Ambrolite-D) and the teeth were equally divided into the four groups (n = 15) for the immersion cycle, following which the teeth were examined for surface microhardness at 7, 14, 21, and 28 days.
Statistical Analysis Used:
ANOVA and post hoc analysis were applied.
Results:
The time and immersion media interaction demonstrated that antitussives produced a significant and gradual loss of surface microhardness on all days (viz., 7, 14, 21, and 28 days), but a statistically significant difference was seen only between 7th and 28th day (P < 0.05).
Conclusions:
The knowledge of the erosive potential of commonly used syrups is mandatory as erosion in children teeth may be associated with dental hypersensitivity, loss of the occlusal vertical dimension, eating difficulties, poor esthetics, pulp exposure, and abscesses. Mouth rinsing with water after taking the medication; addition of calcium, fluoride, or phosphate to formulations; and consumption of the medication at meal times have been recommended to avoid tooth damage that is caused by the regular use of medication.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Drug Dosing: Infants and Children
Acid Suppressive Drugs for Peptic Ulcer Disease: Antacids
However, this neutralization reaction between...
Pharmacokinetics in Pediatric Patients: Drug Distribution

