Related Experiment Video
Updated: Mar 12, 2026

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
Published on: January 17, 2025
A New Wavelet Denoising Method for Selecting Decomposition Levels and Noise Thresholds
Madhur Srivastava1, C Lindsay Anderson2, Jack H Freed3
1National Biomedical Center for Advanced ESR Technology (ACERT) and the Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853 USA.
Abstract:
A new method is presented to denoise 1-D experimental signals using wavelet transforms. Although the state-of- the-art wavelet denoising methods perform better than other denoising methods, they are not very effective for experimental signals. Unlike images and other signals, experimental signals in chemical and biophysical applications for example, are less tolerant to signal distortion and under-denoising caused by the standard wavelet denoising methods. The new method 1) provides a method to select the number of decomposition levels to denoise, 2) uses a new formula to calculate noise thresholds that does not require noise estimation, 3) uses separate noise thresholds for positive and negative wavelet coefficients, 4) applies denoising to the Approximation component, and 5) allows the flexibility to adjust the noise thresholds. The new method is applied to continuous wave electron spin resonance (cw-ESR) spectra and it is found that it increases the signal-to-noise ratio (SNR) by more than 32 dB without distorting the signal, whereas standard denoising methods improve the SNR by less than 10 dB and with some distortion. Also, its computation time is more than 6 times faster.
Related Concept Videos
Downsampling
The Fourier transform of the decimated sequence reveals a combination of scaled and shifted versions of the original spectrum. This...
Deconvolution
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
¹³C NMR: ¹H–¹³C Decoupling
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
Introduction and Methods of Leveling
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
Upsampling

