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Updated: Mar 12, 2026

Establishment and Evaluation of a Porcine Vein Graft Disease Model
Published on: July 25, 2022
Coronary artery bypass grafting with internal thoracic arteries may cause bilateral brachiocephalic vein occlusion,
Keisuke Nakabayashi1, Hiroko Kato1, Ryo Sugiura1
1Department of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.
Insights
Pacemaker implantation failed due to bilateral brachiocephalic vein occlusion 8 years after coronary artery bypass grafting. Surgical implantation was successful, highlighting the need for advanced imaging in complex cases.
Area of Science:
- Cardiology
- Vascular Surgery
- Medical Imaging
Background:
- Increasing prevalence of arrhythmia and ischemic heart disease necessitates pacemaker implantation.
- Brachiocephalic vein occlusion is a known complication post-pacemaker implantation, but its association with prior coronary artery bypass grafting (CABG) is less understood.
- Internal thoracic artery grafts are commonly used in CABG, yet their long-term impact on central venous pathways requires further investigation.
Observation:
- A case of failed percutaneous pacemaker implantation is presented in a patient with bilateral brachiocephalic vein occlusion.
- The occlusion occurred 8 years after undergoing bilateral internal thoracic artery coronary artery bypass grafting.
- Rich collateral venous networks, including the hemiazygos and azygos veins, were noted.
Findings:
- Percutaneous pacemaker implantation was unsuccessful due to complete bilateral brachiocephalic vein occlusion.
- Surgical pacemaker implantation provided a viable alternative in this complex venous anatomy.
- The findings suggest a potential link between bilateral internal thoracic artery usage in CABG and subsequent central venous complications.
Implications:
- This case underscores the importance of considering prior CABG, especially with bilateral internal thoracic artery grafts, when evaluating central venous access for pacemaker implantation.
- Enhanced imaging modalities like contrast CT or venography may be crucial for pre-procedural assessment in such patients.
- Further research is warranted to elucidate the mechanisms and long-term consequences of brachiocephalic vein occlusion following CABG with internal thoracic artery grafts.
Abstract:
The number of patients with arrhythmia and ischaemic heart diseases is increasing. Patients with pacemaker implantation sometimes have brachiocephalic vein occlusion, and several aetiologies have been reported. However, coronary artery bypass grafting using the internal thoracic arteries is not fully discussed in the literature. We present a case of failed percutaneous pacemaker implantation due to bilateral brachiocephalic vein occlusion 8 years after coronary artery bypass grafting using the bilateral internal thoracic arteries. There were rich collateral veins consisting of hemiazygos and azygos veins. We then performed surgical implantation instead. Contrast CT or venography for such patients might be considered.
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