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Updated: Aug 15, 2026

Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
[Developmental bone abnormalities, their variants and the delay of osteogenesis in children with leukemia]
Abstract:
When analyzing the Roentgen documentation of 102 leukaemic children, the prevalence of bone anomalies of the extremities, pelvis and vertebral column was studied. The frequency of the abnormal or unusual findings was compared with that of 660 control subjects. The frequency of osseous anomalies proved to be 2 to 3 times higher in leukaemic children tha in the controls. Considering the number of ossification centers and the presence nutritional canal of vertebrae, in leukaemic children the ossification seemed to be retarded.
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