Peripapillary choroidal thickness in Chinese children using enhanced depth imaging optical coherence tomography
Xi-Shi Wu1, Li-Jun Shen1, Ru-Ru Chen1
1Eye Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Insights
Peripapillary choroidal thickness (PPCT) is thinner in the temporal segments of myopic children. Axial length is negatively correlated with PPCT, suggesting a link between eye growth and choroidal thinning.
Area of Science:
- Ophthalmology
- Optometry
- Pediatric Eye Care
Background:
- Peripapillary choroidal thickness (PPCT) is a key parameter in ocular health.
- Understanding PPCT variations in children is crucial for early detection of eye conditions.
Purpose of the Study:
- To measure PPCT in Chinese children.
- To identify factors influencing PPCT, particularly in relation to myopia.
Main Methods:
- Enhanced depth imaging optical coherence tomography (EDI-OCT) was used to measure PPCT in 70 children (aged 7-18).
- Measurements were taken in six sectors around the optic disc and globally.
- Participants included myopic and non-myopic children with varying refractive errors.
Main Results:
- The mean global PPCT was 165.49±33.76 µm.
- Myopic children showed significantly thinner PPCT in temporal, superotemporal, and inferotemporal segments.
- Axial length was significantly associated with average global, superonasal, and inferonasal PPCT.
Conclusions:
- Myopia in children is associated with thinner PPCT in specific peripapillary regions.
- A negative correlation exists between axial length and PPCT.
- Further research is warranted to explore the relationship between PPCT and myopia progression.
Aim:
To evaluate the peripapillary choroidal thickness (PPCT) in Chinese children, and to analyze the influencing factors.
Methods:
PPCT was measured with enhanced depth imaging optical coherence tomography (EDI-OCT) in 70 children (53 myopes and 17 non-myopes) aged 7 to 18y, with spherical equivalent refractive errors between 0.50 and -5.87 diopters (D). Peripapillary choroidal imaging was performed using circular scans of a diameter of 3.4 mm around the optic disc. PPCT was measured by EDI-OCT in six sectors: nasal (N), superonasal (SN), superotemporal (ST), temporal (T), inferotemporal (IT) and inferonasal (IN), as well as global RNFL thickness (G).
Results:
The mean global PPCT was 165.49±33.76 µm. The temporal, inferonasal, inferotemporal PPCT were significantly thinner than the nasal, superonasal, superotemporal segments PPCT were significantly thinner in the myopic group at temporal, superotemporal and inferotemporal segments. The axial length was significantly associated with the average global (β=-0.419, P=0.014), superonasal (β=-2.009, P=0.049) and inferonasal (β= -2.000, P=0.049) PPCT. The other factors (gender, age, SE) were not significantly associated with PPCT.
Conclusion:
PPCT was thinner in the myopic group at temporal, superotemporal and inferotemporal segments. The axial length was found to be negatively correlated to PPCT. We need more further studies about the relationship between PPCT and myopia.
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