Related Experiment Video

Updated: Mar 12, 2026

Efficient PAM-Less Base Editing for Zebrafish Modeling of Human Genetic Disease with zSpRY-ABE8e
07:31

Efficient PAM-Less Base Editing for Zebrafish Modeling of Human Genetic Disease with zSpRY-ABE8e

Published on: February 17, 2023

1.7K

Modeling and Genome-Editing Brugada Syndrome in a Dish

Hee Cheol Cho1

  • 1Departments of Biomedical Engineering and Pediatrics, Emory University, Atlanta, Georgia.

Journal of the American College of Cardiology
|November 5, 2016
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Brugada syndromearrhythmiasdisease modelgenome editinginduced pluripotent stem cells

More Related Videos

CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts
06:52

CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts

Published on: September 13, 2022

4.1K
In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.4K

Related Experiment Videos

Last Updated: Mar 12, 2026

Efficient PAM-Less Base Editing for Zebrafish Modeling of Human Genetic Disease with zSpRY-ABE8e
07:31

Efficient PAM-Less Base Editing for Zebrafish Modeling of Human Genetic Disease with zSpRY-ABE8e

Published on: February 17, 2023

1.7K
CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts
06:52

CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts

Published on: September 13, 2022

4.1K
In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.4K

Related Concept Videos

CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

2.4K
The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
2.4K

Articles linked to this work by shared authors, journal, and citation graph.

Phosphorus-31 Magnetic Resonance Spectroscopy for Serial Measurements of Cardiac Energetics During Temperature-Controlled Heart Preservation.

Journal of visualized experiments : JoVE·2026

Innate immune activation and mitochondrial ROS induce acute and persistent cardiac conduction system dysfunction after COVID-19.

JCI insight·2025

A highly effective, rodent model of complete heart block by epicardial radiofrequency ablation.

Scientific reports·2025

Tissue elasticity modulates cardiac pacemaker cell automaticity.

American journal of physiology. Heart and circulatory physiology·2025

Transient pacing in pigs with complete heart block via myocardial injection of mRNA coding for the T-box transcription factor 18.

Nature biomedical engineering·2024

Simulated microgravity improves maturation of cardiomyocytes derived from human induced pluripotent stem cells.

Scientific reports·2024

Targeted Assessment in High-Risk Patients With Diabetes to Identify Undiagnosed Heart Failure (TARTAN-HF).

Journal of the American College of Cardiology·2026

AI-ECG Detection of Structural Heart Disease in the Community Setting: Transportability and Spectrum Effects in the PREVUE-VALVE Study.

Journal of the American College of Cardiology·2026

2026 AHA/ACC Clinical Performance and Quality Measures for Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association.

Journal of the American College of Cardiology·2026

Acute Effects of Cannabis Inhalation on Cardiac Ectopy, Physical Activity, Sleep, and Glucose.

Journal of the American College of Cardiology·2026

Intravenous Nicorandil in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary PCI: The CLEAN Randomized Clinical Trial.

Journal of the American College of Cardiology·2026

Implications of the 2026 Versus 2018 ACC/AHA Multisociety Dyslipidemia Guidelines on the Clinical Care of U.S. Adults.

Journal of the American College of Cardiology·2026

Interpretable AI-driven materiomics to decode microenvironmental cues for stem cell immunomodulation.

Bioactive materials·2026

Bile acid triggered release of daunorubicin from silica nanoparticle-stabilized antibubbles.

International journal of pharmaceutics: X·2026

Design and evaluation of a novel peptide-EV complex for targeted Alzheimer's disease therapy.

Journal of drug targeting·2026

Tumor microenvironment-remodeling cell membrane biomimetic nanoplatform for activated imaging and cascade-amplified treatment of breast cancer.

Journal of advanced research·2026

A pH-responsive nanozyme-integrated fibrous biointerface for chemodynamic antibacterial therapy and infected wound healing.

Colloids and surfaces. B, Biointerfaces·2026

Ultrasmall Cerium-EGCG Nanoparticles Ameliorate Sepsis via Macrophage Reprogramming and Ferroptosis Inhibition.

ACS applied materials & interfaces·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us