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Hypertension Is a Risk Factor for Several Types of Heart Disease: Review of Prospective Studies

Yoshihiro Kokubo1, Chisa Matsumoto2

  • 1Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, 5-7-1, Fujishiro-dai, Suita, Osaka, 565-8565, Japan. ykokubo@hsp.ncvc.go.jp.

Advances in Experimental Medicine and Biology
|November 6, 2016
PubMed

Insights

Hypertension significantly increases the risk of various heart diseases, including coronary heart disease and heart failure. Managing blood pressure is crucial for preventing cardiovascular disease and reducing mortality risk.

Area of Science:

  • Cardiovascular Medicine
  • Epidemiology
  • Public Health

Background:

  • Hypertension is a well-established risk factor for mortality and cardiovascular disease (CVD).
  • Previous research predominantly focused on the link between hypertension and coronary/ischemic heart disease.
  • A comprehensive understanding of hypertension's impact on diverse heart conditions is needed.

Purpose of the Study:

  • To systematically review the association between hypertension and a broad spectrum of heart diseases.
  • To consolidate evidence on hypertension's role in conditions beyond coronary heart disease.
  • To identify potential sex-based differences in these associations.

Main Methods:

  • Comprehensive literature review of prospective cohort studies.
  • Analysis of epidemiological data linking hypertension to various cardiovascular conditions.
  • Synthesis of findings regarding specific heart diseases and hypertension.

Main Results:

  • Hypertension is significantly associated with coronary heart disease, heart failure, atrial fibrillation, aortic valvular disease, sudden cardiac death, sick sinus syndrome, left ventricular hypertrophy, and abdominal aortic aneurysms.
  • These associations were generally stronger in men.
  • The review identified a wide range of cardiovascular conditions linked to elevated blood pressure.

Conclusions:

  • Hypertension is a critical risk factor for numerous cardiovascular diseases.
  • Preventive strategies targeting hypertension may substantially reduce the burden of heart disease.
  • Lowering blood pressure is a key intervention for cardiovascular risk reduction.

Keywords:
EpidemiologyHeart diseaseHypertensionProspective studiesRisk factors

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