Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

15.5K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
15.5K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

9.8K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
9.8K
Stringent Response in E. coli01:23

Stringent Response in E. coli

447
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
447

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

#infertility education on Instagram: A Reliability Analysis in Brazil Using the DISCERN Instrument.

JBRA assisted reproduction·2026
Same author

Testing the use of a biomarker (PlGF) to evaluate superimposed preeclampsia in pregnant women with chronic hypertension (B.I.P.E.S.): a randomized clinical trial study protocol.

BMC pregnancy and childbirth·2025
Same author

Melatonin promotes cytotoxicity while reducing cell motility and antioxidant defenses in ovarian cancer cell lines.

Toxicology reports·2025
Same author

Impact of embryo storage time after vitrification on pregnancy and implantation rates.

JBRA assisted reproduction·2025
Same author

Optimal gonadotropin-releasing hormone agonist dosage for oocyte maturation in low-prognosis patients: interim analysis of a randomized controlled trial in Patient-Oriented Strategies Encompassing IndividualizeD Oocyte groups 3 and 4.

Fertility and sterility·2025
Same author

Hemophagocytic Lymphohistiocytosis Secondary to Visceral Leishmaniasis: A Case Report.

Cureus·2025

Related Experiment Video

Updated: Mar 12, 2026

Flash-and-Freeze: A Novel Technique to Capture Membrane Dynamics with Electron Microscopy
10:01

Flash-and-Freeze: A Novel Technique to Capture Membrane Dynamics with Electron Microscopy

Published on: May 1, 2017

14.7K

Freeze-all cycle for all normal responders?

Matheus Roque1,2, Marcello Valle3, Fernando Guimarães3

  • 1ORIGEN-Center for Reproductive Medicine, Avenida Rodolfo de Amoedo, 140-Barra da Tijuca, Rio de Janeiro, Brazil. matheusroque@hotmail.com.

Journal of Assisted Reproduction and Genetics
|November 7, 2016
PubMed
Summary

The freeze-all strategy may improve in vitro fertilization outcomes for normal responders. However, its benefits diminish with lower ovarian response, showing no advantage for patients with poorer ovarian response.

Keywords:
Delayed frozen-thawed embryo transferElective frozen-thawed embryo transferEmbryo cryopreservationFreeze-all policyIVF/ICSI

More Related Videos

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
10:10

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

Published on: October 18, 2011

13.1K
Plunge Freezing: A Tool for the Ultrastructural and Immunolocalization Studies of Suspension Cells in Transmission Electron Microscopy
13:35

Plunge Freezing: A Tool for the Ultrastructural and Immunolocalization Studies of Suspension Cells in Transmission Electron Microscopy

Published on: May 5, 2017

11.6K

Related Experiment Videos

Last Updated: Mar 12, 2026

Flash-and-Freeze: A Novel Technique to Capture Membrane Dynamics with Electron Microscopy
10:01

Flash-and-Freeze: A Novel Technique to Capture Membrane Dynamics with Electron Microscopy

Published on: May 1, 2017

14.7K
Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
10:10

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

Published on: October 18, 2011

13.1K
Plunge Freezing: A Tool for the Ultrastructural and Immunolocalization Studies of Suspension Cells in Transmission Electron Microscopy
13:35

Plunge Freezing: A Tool for the Ultrastructural and Immunolocalization Studies of Suspension Cells in Transmission Electron Microscopy

Published on: May 5, 2017

11.6K

Area of Science:

  • Reproductive Endocrinology
  • In Vitro Fertilization
  • Ovarian Response

Background:

  • Controlled Ovarian Stimulation (COS) protocols are standard in IVF.
  • The freeze-all strategy aims to optimize pregnancy outcomes by cryopreserving embryos.
  • Individualized embryo transfer (iET) is being explored to tailor treatment based on patient response.

Purpose of the Study:

  • To evaluate the efficacy of the freeze-all strategy in normal responders.
  • To determine if the freeze-all strategy benefits patients regardless of their ovarian response.
  • To explore the feasibility of an individualized embryo transfer (iET) approach based on ovarian response.

Main Methods:

  • Observational cohort study of 938 IVF cycles.
  • Patients underwent COS using a GnRH antagonist protocol.
  • Comparison of fresh embryo transfer (n=523) versus freeze-all cycles (n=415) in subgroups based on oocyte retrieval (4-9 vs. 10-15).

Main Results:

  • In patients retrieving 10-15 oocytes, freeze-all cycles showed significantly higher implantation (30.1% vs. 22.1%) and ongoing pregnancy rates (47% vs. 34%) compared to fresh transfers (P<0.05).
  • In patients retrieving 4-9 oocytes, no significant differences in implantation or ongoing pregnancy rates were observed between fresh and freeze-all groups.
  • The benefits of the freeze-all strategy were less pronounced in the lower oocyte yield group.

Conclusions:

  • The freeze-all policy may enhance IVF outcomes in normal responders.
  • The advantages of the freeze-all strategy decrease as ovarian response declines.
  • Patients with poorer ovarian response do not appear to benefit from the freeze-all strategy.