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Oxidation and O-dealkylation of sulphamonomethoxine by the turtle Pseudemys scripta elegans
T B Vree1, J B Vree, N Beneken Kolmer
1Department of Clinical Pharmacy, Sint Radboud Hospital, Nijmegen, The Netherlands.
The Veterinary Quarterly
|July 1, 1989
Abstract:
Sulphamonomethoxine is O-demethylated at the 6 position and oxidised at the 2 position of the pyrimidine substituent by Pseudemys scripta elegans. No N4-acetylation takes place. The yield of the oxidation reaction is twice that of the O-demethylation reaction.