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Cationic liposomes induce cell necrosis through lysosomal dysfunction and late-stage autophagic flux inhibition

Kaixuan Yang1,2,3, Ying Lu1, Fangyuan Xie1,4

  • 1Department of Pharmaceutical Sciences, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.

Nanomedicine (London, England)
|November 8, 2016
PubMed
Abstract

Keywords:
autophagic fluxcationic liposomescellular toxicitygene therapylysosome membrane permeabilizationnecrosis

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