Related Experiment Video
Updated: Mar 12, 2026

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels
Published on: May 18, 2009
Cell-Like P Systems With Channel States and Symport/Antiport Rules
Abstract:
Cell-like P systems with symport/antiport rules are inspired by the structure of a cell and the way of communicating substances through membrane channels between neighboring regions. In this work, channel states are introduced into cell-like P systems with symport/antiport rules, and we call this variant of communication P systems as cell-like P systems with channel states and symport/antiport rules. In such P systems, at most one channel is established between neighboring regions, each channel associates with one state in order to control communication at each step, and rules are used in a sequential manner: on each channel at most one rule can be used at each step. The computational power of such P systems is investigated. Specifically, we show that cell-like P systems with two states and using uniport rules, or with any number of states and using antiport rules of length two, are able to compute only finite sets of non-negative integers. We further prove that cell-like P systems with two membranes are as powerful as Turing machines when channel states and symport/antiport rules are suitably combined. The results show that channel states are a feature that can increase the computational power of cell-like P systems with symport/antiport rules.
Related Concept Videos
Membrane Asymmetry Regulating Transporters
Flippase
Eukaryotic flippases are type-IV P-type ATPases or P4-ATPases belonging to P-type ATPase family proteins that are membrane-bound pumps involved in the ATP-mediated transport of ions and molecules across the membrane. Flippases flip specific phospholipids from the outer to the inner leaflet of a membrane. All P4-ATPases have one...
ATP Driven Pumps II: P-type Pumps
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
Membrane Transporters
Transporters are mainly composed of alpha-helices, built from bundles of ten or more helices traversing the plasma membrane. The solute-binding sites are located midway, where some of the helices are broken or distorted, making space for the binding site through...
Ion Channels
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
Electrochemical Gradient and Channel Proteins: An Overview
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell. This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
Mechanically-gated Ion Channels

