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Updated: Mar 12, 2026
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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
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Transfusion transmitted dengue: One donor infects two patients
Farheen Karim1, Nadia Nasir1, Bushra Moiz1
1Section of Hematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi, Pakistan.
Summary
Transfusion-transmitted dengue is possible, as two surgical patients likely contracted the infection from the same blood donor. This highlights dengue
Area of Science:
- Virology
- Transfusion Medicine
- Infectious Diseases
Background:
- Dengue virus poses a significant risk to blood transfusion safety, particularly in endemic areas.
- Blood components can harbor and transmit the dengue virus.
Observation:
- Two surgical patients developed symptoms suggestive of dengue fever post-transfusion.
- Both patients received blood components derived from a single, common donor.
Findings:
- This case suggests a potential transmission of dengue virus through blood transfusion from a single donor.
- The clinical presentation in the recipients was consistent with dengue infection.
Implications:
- Dengue virus transmission via blood transfusion is a critical concern for blood supply safety.
- Screening blood donors for dengue virus in endemic regions may be warranted to prevent transfusion-transmitted infections.
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