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Coordinate based meta-analysis does not show grey matter atrophy in narcolepsy

C R Tench1, Radu Tanasescu2, W J Cottam3

  • 1Division of Clinical Neurosciences, Clinical Neurology, University of Nottingham, Queen's Medical Centre, Nottingham, UK.

Neuroscience and Biobehavioral Reviews
|November 10, 2016
PubMed
Summary

No abstract available in PubMed .

Keywords:
AtrophyCoordinate based meta-analysisNarcolepsyVoxel based morphometry

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Narcolepsy01:07

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Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
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Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
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