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Resting Heart Rate and Aortic Stiffness in Normotensive Adults

Jeongok G Logan1, Suk-Sun Kim2

  • 1School of Nursing, University of Virginia, VA, USA.

Korean Circulation Journal
|November 10, 2016
PubMed

Insights

Higher resting heart rate is linked to increased arterial stiffness in healthy adults. This finding suggests heart rate may play a role in cardiovascular health, even without hypertension.

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Public Health

Background:

  • Large-artery stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), predicts cardiovascular disease (CVD).
  • Resting heart rate (RHR) is a vital sign associated with CVD morbidity and mortality.
  • Previous research linked RHR and cfPWV only in hypertensive individuals, leaving the relationship in normotensive subjects unknown.

Purpose of the Study:

  • To investigate the relationship between resting heart rate and arterial stiffness in normotensive adults.
  • To determine if RHR is an independent predictor of cfPWV in a non-hypertensive population.

Main Methods:

  • 102 healthy Korean American adults (ages 20-60) participated.
  • Resting heart rate was measured using an automated device after a 10-minute rest.
  • Arterial stiffness was assessed using carotid-femoral pulse wave velocity (cfPWV) with the SphygmoCor device.

Main Results:

  • The average RHR was 61.91 bpm and the average cfPWV was 6.99 m/s.
  • Multiple regression analysis revealed RHR as a significant predictor of cfPWV.
  • Each 1 bpm increase in RHR was associated with an approximate 0.02 m/s increase in cfPWV, independent of age, BMI, and mean arterial pressure.

Conclusions:

  • Elevated resting heart rate is independently associated with increased arterial stiffness in normotensive adults.
  • Arterial stiffness may mediate the prognostic value of heart rate for cardiovascular outcomes.
  • These findings highlight RHR as a potential indicator of vascular health in the general population.
Abstract

Keywords:
Arterial stiffnessCardiovascular diseasesHeart rateHypertensionPulse wave velocity

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