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Extensive coronary and systemic arterial aneurysm development in severe refractory Kawasaki disease

Niall Johnston1, David Coleman1, Colin J McMahon1

  • 1Department of Paediatric Cardiology,Our Lady's Children's Hospital,Crumlin,Dublin,Ireland.

Cardiology in the Young
|November 11, 2016
PubMed

Insights

Atypical Kawasaki disease in an infant led to severe coronary aneurysms and thrombosis. The condition also caused widespread arterial aneurysms in the systemic circulation, highlighting disease severity.

Area of Science:

  • Pediatric Cardiology
  • Rheumatology
  • Infectious Diseases

Background:

  • Kawasaki disease is a leading cause of acquired pediatric heart disease.
  • Atypical presentations can delay diagnosis and treatment, increasing complication risk.

Observation:

  • An 8-week-old infant presented late with severe, refractory atypical Kawasaki disease.
  • The infant developed giant coronary arterial aneurysms and coronary thrombosis.

Findings:

  • Extensive bilateral arterial aneurysms were observed throughout the infant's systemic circulation.
  • This case demonstrates a rare and severe manifestation of atypical Kawasaki disease.

Implications:

  • Highlights the importance of early recognition of atypical Kawasaki disease presentations.
  • Suggests potential for widespread vascular involvement beyond coronary arteries.
  • Underscores the need for vigilant monitoring and aggressive management in severe cases.

Keywords:
Kawasaki diseasethrombosisvasculitis

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