Related Experiment Video

Updated: Mar 12, 2026

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
07:37

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae

Published on: April 30, 2018

15.2K

A case of Degos disease in pregnancy

Sapna Sharma1, Barbara Brennan1, Ray Naden2

  • 1Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, McMaster University, Hamilton, ON, Canada.

Obstetric Medicine
|November 11, 2016
PubMed

Insights

Degos disease, a rare systemic vaso-occlusive disorder, can be managed during pregnancy. This case study shows an uncomplicated pregnancy with no adverse effects on the mother or baby.

Area of Science:

  • Vascular Medicine
  • Obstetrics
  • Rare Diseases

Background:

  • Degos disease is a rare systemic vaso-occlusive disorder with uncertain pathophysiology.
  • Fewer than 200 cases are documented, with limited information on its course during pregnancy.

Observation:

  • This report details the first case of systemic Degos disease throughout a pregnancy.
  • The patient was diagnosed pre-pregnancy and received continuous monitoring.

Findings:

  • The pregnancy proceeded without exacerbation of Degos disease.
  • Both the pregnancy and the infant experienced no adverse outcomes.

Implications:

  • This case suggests pregnancy may be uncomplicated in women with Degos disease.
  • Further research is needed to understand Degos disease management in pregnancy.

Keywords:
General medicinehigh-risk pregnancy

More Related Videos

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.4K
Transabdominal Ultrasound for Pregnancy Diagnosis in Reeves' Muntjac Deer09:26

Transabdominal Ultrasound for Pregnancy Diagnosis in Reeves' Muntjac Deer

Published on: January 7, 2014

10.9K

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.1K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.3K
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.4K
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
3.7K
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
504
Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
4.4K