[Non-fatal case of H1n1 influenza encephalopathy in a pediatric patient]

Related Experiment Video

Updated: Mar 12, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

12.0K

María Del Carmen Valdivia-Tapia1, Nilton Yhuri Carreazo2,3

  • 1Servicio de Pediatría. Hospital de Emergencias Pediátricas. Lima, Perú.

Revista Peruana De Medicina Experimental Y Salud Publica
|November 11, 2016
PubMed

Insights

Influenza A H1N1 infection can cause severe neurological symptoms in children, including seizures and intracranial hypertension. Prompt supportive care can lead to favorable outcomes, even without antiviral treatment.

Area of Science:

  • Pediatric Neurology
  • Infectious Diseases

Background:

  • Influenza A virus infections are common in children.
  • Neurological complications of influenza can be severe and varied.

Observation:

  • A 2-year-old girl presented with fever, upper respiratory symptoms, and focal seizures.
  • Seizures progressed, leading to increased intracranial pressure.

Findings:

  • Polymerase chain reaction confirmed influenza A H1N1 infection.
  • The patient experienced focal hemispheric seizures and intracranial hypertension.

Implications:

  • This case highlights the potential for severe neurological manifestations of H1N1 influenza in pediatric patients.
  • Supportive care alone may be sufficient for managing H1N1-associated neurological complications in some children.

More Related Videos

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

947
Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection07:45

Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection

Published on: September 19, 2025

582

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
308
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
349