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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells
P S Kulkarni1, M K Haldar1, M I Confeld2
1Department of Pharmaceutical Science, North Dakota State University, Fargo ND, USA.
Polymer Chemistry
|November 12, 2016
Abstract:
Mitochondria is an attractive target to deliver anticancer drugs. We have synthesized a cationic triphenylphosphonium ion conjugated fluorescent polymer which self-assembles into nanosized polymersomes and targets the encapsulated anticancer drug doxorubicin to cancer cell mitochondria.
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