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Updated: Mar 12, 2026

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
Published on: December 15, 2023
Alzheimer's Disease Detection by Pseudo Zernike Moment and Linear Regression Classification
Shui-Hua Wang, Sidan Du, Yin Zhang
1School of Computer Science and Technology, Nanjing Normal University, Nanjing, Jiangsu 210023,. China.
Aim:
This study presents an improved method based on "Gorji et al. Neuroscience. 2015" by introducing a relatively new classifier-linear regression classification.
Method:
Our method selects one axial slice from 3D brain image, and employed pseudo Zernike moment with maximum order of 15 to extract 256 features from each image. Finally, linear regression classification was harnessed as the classifier.
Results:
The proposed approach obtains an accuracy of 97.51%, a sensitivity of 96.71%, and a specificity of 97.73%.
Conclusion:
Our method performs better than Gorji's approach and five other state-of-the-art approaches.
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