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Updated: Mar 12, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
[Anaphylaxis in children: What pediatricians should know]
1Service de pédiatrie, pavillon médicochirurgical de pédiatrie, boulevard Lacordaire, 59056 Roubaix, France; Unité de pneumologie et allergologie pédiatriques, université Lille 2, hôpital Jeanne-de-Flandre, CHRU Lille, 2, avenue Oscar-Lambret, 59037 Lille, France.
Abstract:
Anaphylaxis is a severe potentially life-threatening allergic emergency that has been increasing over the last two decades, especially in young children. Anaphylaxis deaths remain rare, in particular in children, and their frequency is stable during this period. Food is the main anaphylaxis trigger in children, notably to cow's milk, peanuts, and tree nuts. In infants, the recognition of anaphylaxis may be difficult. Vomiting, urticaria, and laryngeal edema are more frequent at this age. Cardiovascular involvement is rare, most often encountered in adolescence. A history of asthma or atopy, allergy to particular foods such as peanuts and tree nuts, and adolescence are some risk factors for anaphylaxis and more severe reactions. First-line treatment is intramuscular adrenaline for all patients experiencing anaphylaxis. There are no absolute contra-indications. Guidelines for the prescription of the adrenaline auto-injector and for establishing a personalized care project in allergic children at school have recently been updated. Recognition of anaphylaxis and treatment should also be improved.
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