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Multiple ectopic calcifications in subcutaneous tissues with chronic renal failure: A case report
RongKai Zhang1, GuoWei Li1, LuKun Yang2
1Department of Orthopaedics, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
International Journal of Surgery Case Reports
|November 14, 2016
Summary
Complete surgical excision is a viable treatment for tumoral calcinosis, a rare condition involving ectopic calcifications. Early and thorough removal of these calcium phosphate deposits can prevent recurrence in patients with chronic renal failure.
Area of Science:
- Nephrology
- Orthopedic Surgery
- Dermatology
Background:
- Tumoral calcinosis is a rare syndrome characterized by ectopic calcification of calcium phosphate in periarticular tissues.
- This case presents a unique instance of multiple subcutaneous calcifications in a hemodialysis patient with a history of multiple surgeries.
Purpose of the Study:
- To evaluate the efficacy of surgical excision in managing multiple ectopic calcifications in a hemodialysis patient.
- To assess the impact of subtotal parathyroidectomy on ectopic calcification recurrence in chronic renal failure.
Main Methods:
- Surgical excision of ectopic calcifications in the left shoulder, right buttock, and right thigh.
- Subtotal parathyroidectomy with forearm autotransplantation.
- Follow-up assessment for recurrence at surgical sites.
Main Results:
- Complete excision led to no recurrence in the left shoulder, right buttock, and right thigh.
- Incomplete excision in the right shoulder resulted in recurrence, necessitating further surgery.
- Parathyroidectomy reduced PTH levels but did not alter calcium or phosphorus levels, nor inhibit calcification recurrence.
Conclusions:
- Early and complete surgical excision is a recommended therapeutic option for tumoral calcinosis when conservative measures fail.
- Surgical management of ectopic calcifications in hemodialysis patients requires careful consideration of complete excision to prevent recurrence.
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