Related Experiment Video
Updated: Mar 12, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Advocating for Childcare Employee Single-Dose Tdap Vaccination to Combat Infant Pertussis
Insights
Pertussis (whooping cough) is surging, endangering infants. Cocooning, or vaccinating close contacts like childcare workers with the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine, is crucial for protection.
Area of Science:
- Public Health
- Immunology
- Pediatrics
Background:
- Pertussis (whooping cough) incidence is at a record high, posing a significant threat to infants under 12 months.
- Infants are highly vulnerable to severe respiratory illness, hospitalization, and death from pertussis.
- Diminished herd immunity necessitates strategies like cocooning to protect vulnerable populations.
Purpose of the Study:
- To highlight the critical need for Tdap vaccination among childcare employees to protect infants.
- To explore the role of advanced practice nurses in advocating for state-level Tdap vaccination policies in childcare settings.
- To identify initial advocacy steps for advanced practice registered nurses.
Main Methods:
- Review of current pertussis incidence and infant vulnerability data.
- Analysis of existing state childcare regulations regarding Tdap vaccination for employees.
- Discussion of advocacy strategies for advanced practice nurses.
Main Results:
- Only 11 states have regulations mandating Tdap vaccination for childcare employees.
- There is a significant gap between recommendations and implementation of Tdap vaccination for childcare workers.
- Advanced practice nurses are uniquely positioned to lead advocacy efforts.
Conclusions:
- Childcare employee Tdap vaccination is essential for infant pertussis prevention.
- State-level advocacy is required to improve vaccination rates among childcare workers.
- Advanced practice nurses can drive policy change to protect vulnerable infants.
Abstract:
Incidence rates of pertussis have been higher over the past 5 years than at any time since the first pertussis vaccine became widely available, with infants younger than 12 months old being particularly vulnerable. Once infected, infants may experience severe respiratory symptoms and incur high rates of hospitalization, and they account for the vast majority of pertussis-related deaths each year. With the diminished effectiveness of herd immunity, experts increasingly rely on cocooning to protect at-risk populations against infectious diseases such as pertussis. Cocooning calls for vaccination of all close contacts of vulnerable individuals, including childcare employees. Despite government recommendations, only 11 states address employee tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination in their childcare regulations. Advanced practice nurses can play a significant role in protecting infants younger than 12 months old through initiating and supporting advocacy efforts at the state level for childcare employee Tdap vaccination. This article explores initial advocacy steps to be taken by advanced practice registered nurses to address this important issue.
More Related Videos
08:03Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
Published on: April 15, 2014
06:32Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
Published on: September 19, 2016
Related Concept Videos
Vaccinations
Drug Dosing: Infants and Children
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include: