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Related Experiment Video

Updated: Mar 12, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
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Current Advances in Lanthanide-Doped Upconversion Nanostructures for Detection and Bioapplication.

Cailing Chen1, Chunguang Li1, Zhan Shi1

  • 1State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry Jilin University Changchun 130012 P. R. China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|November 15, 2016
PubMed
Summary

Lanthanide-doped upconversion nanostructures offer unique advantages for various applications. This review details their mechanisms, synthesis, and promising uses in detection, bioimaging, and therapy.

Keywords:
bioapplicationdetectionmechanismsynthesisupconversion luminescence

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Optics

Background:

  • Lanthanide-doped upconversion nanostructures are advanced nanomaterials exhibiting unique luminescence properties.
  • Upconversion luminescence involves absorbing multiple low-energy photons to emit a single high-energy photon.
  • These nanostructures possess advantages like minimal background noise, extended lifetimes, and enhanced tissue penetration.

Purpose of the Study:

  • To review current advancements in lanthanide-doped upconversion nanostructures.
  • To cover fundamental luminescence mechanisms, synthesis, and modification techniques.
  • To highlight design strategies like core-shell nanoparticles and nanocomposites.

Main Methods:

  • Review of existing literature on synthesis and fabrication methods.
  • Analysis of luminescence mechanisms and material properties.
  • Exploration of design principles for advanced nanostructures.

Main Results:

  • Upconversion nanostructures demonstrate significant potential across diverse fields.
  • Core-shell nanoparticles and nanocomposites offer tunable properties.
  • Key applications include anticounterfeiting, solar cells, detection, bioimaging, and therapy.

Conclusions:

  • Understanding upconversion nanostructures is crucial for practical applications.
  • Continued research will unlock further potential in detection, bioimaging, and therapy.
  • These materials represent a significant frontier in nanomaterials science.