Related Experiment Video
Updated: Mar 12, 2026
06:11
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
10.4K
The Danish Head and Neck Cancer database
Jens Overgaard1, Aleksandar Jovanovic1, Christian Godballe2
1Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus.
Clinical Epidemiology
|November 16, 2016
Summary
Over 45 years of head and neck cancer data show improved outcomes due to multidisciplinary treatment strategies and clinical trials. This Danish Head and Neck Cancer database provides a foundation for future research and enhanced patient care.
Area of Science:
- Oncology
- Clinical Epidemiology
- Health Services Research
Background:
- The Danish Head and Neck Cancer database is a nationwide clinical quality registry with prospective data since the early 1960s.
- Multidisciplinary treatment strategies are crucial for managing head and neck cancers.
- Understanding treatment outcomes is essential for advancing cancer care and clinical trials.
Approach:
- Analysis of prospective data from the Danish Head and Neck Cancer database, spanning over 45 years.
- Inclusion of patients diagnosed with squamous cell carcinoma of the larynx, pharynx, oral cavity, neck nodes, nasal sinuses, salivary glands, or thyroid gland.
- Comprehensive data collection including symptoms, etiological factors, diagnostic evaluations, treatment details, follow-up, relapse, and mortality.
Key Points:
- Over 33,000 patients' data have been recorded, demonstrating substantial improvements in treatment outcomes.
- The database facilitated the implementation of national guidelines through continuous clinical trials.
- Analysis revealed the impact of reduced waiting times, changing epidemiology, comorbidity, and socioeconomic factors on treatment outcomes.
Conclusions:
- Half a century of data registration has significantly improved the understanding and treatment of head and neck cancer.
- The database serves as a vital resource for both national and international research and clinical practice.
- Continued data collection and analysis are fundamental for further advancements in head and neck cancer management.
