Evaluation of the extent of nursing involvement required with home pentamidine isethionate infusions

A retrospective review of 20 patients was undertaken to evaluate the extent of nursing involvement required in patients receiving daily Pentamidine infusions. The population was divided into two groups: a) nurse-administered infusions, and b) self-administered infusions. Both groups were evaluated for: 1. Incidence and severity of side effects; 2. Prophylactic measures; 3. Length of infusion and/or nursing visit. A protocol was developed for self-administration of Pentamidine and criteria established for patients to qualify for this independent responsibility. With established protocols and comprehensive patient education, select individuals can safely administer Pentamidine at home with less nursing involvement than previously recognized.