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Photocages for protection and controlled release of bioactive compounds

I Aparici-Espert1, M C Cuquerella1, C Paris1

  • 1Instituto Universitario Mixto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Consejo Superior de Investigaciones Científicas, Avda de los Naranjos s/n, 46022 Valencia, Spain. lvirgini@itq.upv.es mmiranda@qim.upv.es.

Chemical Communications (Cambridge, England)
|November 17, 2016
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Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
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