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    Global immunization coverage for essential vaccines like DTP3 and MCV1 remains stable. However, significant disparities in vaccine access persist, particularly by country income, highlighting the need for improved equity in immunization programs.

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    Area of Science:

    • Public Health
    • Epidemiology
    • Global Health

    Background:

    • The World Health Organization (WHO) initiated the Expanded Program on Immunization in 1974 to combat six major vaccine-preventable diseases.
    • Routine infant immunization is a cornerstone of global public health strategies.
    • Vaccine coverage rates are critical indicators of public health system performance.

    Purpose of the Study:

    • To assess global immunization coverage trends for key vaccines between 2010 and 2015.
    • To evaluate the progress of newer and underused vaccines.
    • To identify disparities in vaccine coverage across different regions and income levels.

    Main Methods:

    • Utilized 2015 WHO and UNICEF estimates for global vaccine coverage.
    • Analyzed coverage data for diphtheria-tetanus-pertussis (DTP3), measles-containing vaccines (MCV1 and MCV2), and polio vaccine (Pol3).
    • Compared coverage rates for rotavirus, pneumococcal conjugate vaccine (PCV), rubella, Haemophilus influenzae type b (Hib), and hepatitis B (HepB3) vaccines.

    Main Results:

    • Stable global coverage for DTP3 (84%-86%), MCV1, and Pol3 since 2010.
    • Increased global coverage for the second dose of measles-containing vaccine (MCV2) from 39% to 43% (by age 2) and 58% to 61% (all ages).
    • Higher coverage in 2015 compared to 2010 for newer vaccines like rotavirus, PCV, rubella, Hib, and HepB3.
    • Significant variations in coverage by WHO Region, country, district, and income classification.

    Conclusions:

    • While overall immunization coverage shows stability and improvement for some vaccines, significant inequities in access persist.
    • Addressing disparities in vaccine access is crucial for achieving and sustaining high global immunization coverage.
    • Enhanced equity is necessary to ensure protection against vaccine-preventable diseases for all populations.