Related Experiment Video
Updated: Mar 11, 2026

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Prediction of fluid responsiveness: an update
Xavier Monnet1, Paul E Marik2, Jean-Louis Teboul3
1Medical Intensive Care Unit, Bicêtre Hospital, Paris-Sud University Hospitals, Inserm UMR_S999, Paris-Sud University, 78, rue du Général Leclerc, 94 270, Le Kremlin-Bicêtre, France. xavier.monnet@aphp.fr.
Predicting fluid responsiveness is crucial in acute circulatory failure. Dynamic tests, unlike static measures, help clinicians avoid fluid overload and make informed decisions about fluid administration.
Area of Science:
- Critical Care Medicine
- Cardiovascular Physiology
Background:
- Fluid administration in acute circulatory failure requires careful consideration due to risks of overload.
- Static preload markers like central venous pressure are unreliable for predicting fluid responsiveness.
- Dynamic physiological tests offer a more accurate approach to fluid management.
Approach:
- Dynamic tests assess cardiac output response to transient preload changes.
- Methods include passive leg raising, end-expiratory occlusion, and pulse/stroke volume variations.
- These techniques leverage heart-lung interactions or small fluid challenges.
Key Points:
- Dynamic tests are superior to static measures for guiding fluid therapy.
- Passive leg raising and end-expiratory occlusion are well-supported dynamic methods.
- These tests help prevent fluid overload and optimize cardiac output.
Conclusions:
- Clinicians should utilize dynamic tests to predict fluid responsiveness in critically ill patients.
- Choosing the appropriate dynamic test depends on patient status and monitoring capabilities.
- Informed fluid management decisions improve patient outcomes in circulatory failure.
Related Concept Videos
Characteristics of Fluids
Body Water Content and Fluid Compartments
Fluid Pressure
According to Pascal's law, a fluid at rest will generate equal pressure in all directions. This pressure is measured as a force per unit area, and its magnitude depends on the fluid's specific...
Pressure of Fluids
The Fluid Mosaic Model
Types of Fluids
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and...

